Large Language Models (LLMs) have been positioned as having the potential to expand access to health information in the Global South, yet their evaluation remains heavily dependent on benchmarks designed around Western norms. We present insights from a preliminary benchmarking exercise with a chatbot for sexual and reproductive health (SRH) for an underserved community in India. We evaluated using HealthBench, a benchmark for conversational health models by OpenAI. We extracted 637 SRH queries from the dataset and evaluated on the 330 single-turn conversations. Responses were evaluated using HealthBench's rubric-based automated grader, which rated responses consistently low. However, qualitative analysis by trained annotators and public health experts revealed that many responses were actually culturally appropriate and medically accurate. We highlight recurring issues, particularly a Western bias, such as for legal framing and norms (e.g., breastfeeding in public), diet assumptions (e.g., fish safe to eat during pregnancy), and costs (e.g., insurance models). Our findings demonstrate the limitations of current benchmarks in capturing the effectiveness of systems built for different cultural and healthcare contexts. We argue for the development of culturally adaptive evaluation frameworks that meet quality standards while recognizing needs of diverse populations.

Low-resource countries represent over 90% of maternal deaths, with Pakistan among the top four countries contributing nearly half in 2023. Since these deaths are mostly preventable, large language models (LLMs) can help address this crisis by automating health communication and risk assessment. However, sexual and reproductive health (SRH) communication in conservative contexts often relies on indirect language that obscures meaning, complicating LLM-based interventions. We conduct a two-stage study in Pakistan: (1) analyzing data from clinical observations, interviews, and focus groups with clinicians and patients, and (2) evaluating the interpretive capabilities of five popular LLMs on this data. Our analysis identifies two axes of communication (referential domain and expression approach) and shows LLMs struggle with semantic drift, myths, and polysemy in clinical interactions. We contribute: (1) empirical themes in SRH communication, (2) a categorization framework for indirect communication, (3) evaluation of LLM performance, and (4) design recommendations for culturally-situated SRH communication.

We introduce HealthDial, a dialogue authoring tool that helps healthcare providers and educators create virtual agents that deliver health education and counseling to patients over multiple conversations. HealthDial leverages large language models (LLMs) to automatically create an initial session-based plan and conversations for each session using text-based patient health education materials as input. Authored dialogue is output in the form of finite state machines for virtual agent delivery so that all content can be validated and no unsafe advice is provided resulting from LLM hallucinations. LLM-drafted dialogue structure and language can be edited by the author in a no-code user interface to ensure validity and optimize clarity and impact. We conducted a feasibility and usability study with counselors and students to test our approach with an authoring task for cancer screening education. Participants used HealthDial and then tested their resulting dialogue by interacting with a 3D-animated virtual agent delivering the dialogue. Through participants' evaluations of the task experience and final dialogues, we show that HealthDial provides a promising first step for counselors to ensure full coverage of their health education materials, while creating understandable and actionable virtual agent dialogue with patients.

While Artificial Intelligence (AI) shows promise in healthcare applications, existing conversational systems often falter in complex and sensitive medical domains such as Sexual and Reproductive Health (SRH). These systems frequently struggle with hallucination and lack the specialized knowledge required, particularly for sensitive SRH topics. Furthermore, current AI approaches in healthcare tend to prioritize diagnostic capabilities over comprehensive patient care and education. Addressing these gaps, this work at the UNC School of Nursing introduces SARHAchat, a proof-of-concept Large Language Model (LLM)- based chatbot. SARHAchat is designed as a reliable, user-centered system integrating medical expertise with empathetic communication to enhance SRH care delivery. Our evaluation demonstrates SARHAchat's ability to provide accurate and contextually appropriate contraceptive counseling while maintaining a natural conversational flow. The demo is available at https://sarhachat.com/.

Due to the limits of science and its steep learning curve, we must rely on the expertise of others to develop our knowledge and skills.26 Toward this end, social media platforms have revolutionized how netizens--users who are actively engaged in online communities--gain knowledge and skills by facilitating the exchange of costless information with the public (for example, followers or influencers). Businesses around the world also use these platforms along with tools based on generative artificial intelligence (GenAI) to craft synthetic media, hoping to grow revenue by attracting more customers and improving their online experience.28 Generative AI tools can empower cyber threats and have cyberpsychological effects on netizens, allowing malicious actors to craft deepfakes in the form of disinformation, misinformation, and malinformation. Service providers not only must enhance GenAI tools to reduce hallucinations, but they also have a statutory duty to mitigate data-driven biases.

Low back pain (LBP) is a leading cause of disability globally. Following the onset of LBP and subsequent treatment, adequate patient education is crucial for improving functionality and long-term outcomes. Despite advancements in patient education strategies, significant gaps persist in delivering personalized, evidence-based information to patients with LBP. Recent advancements in large language models (LLMs) and generative artificial intelligence (GenAI) have demonstrated the potential to enhance patient education. However, their application and efficacy in delivering educational content to patients with LBP remain underexplored and warrant further investigation. In this study, we introduce a novel approach utilizing LLMs with Retrieval-Augmented Generation (RAG) and few-shot learning to generate tailored educational materials for patients with LBP. Physical therapists manually evaluated our model responses for redundancy, accuracy, and completeness using a Likert scale. In addition, the readability of the generated education materials is assessed using the Flesch Reading Ease score. The findings demonstrate that RAG-based LLMs outperform traditional LLMs, providing more accurate, complete, and readable patient education materials with less redundancy. Having said that, our analysis reveals that the generated materials are not yet ready for use in clinical practice. This study underscores the potential of AI-driven models utilizing RAG to improve patient education for LBP; however, significant challenges remain in ensuring the clinical relevance and granularity of content generated by these models.

Comprehensive sex education (SE) is crucial in promoting sexual health and responsible behavior among students, particularly in elementary schools. Despite its significance, teaching SE can be challenging due to students' attitudes, shyness, and emotional barriers. Socially assistive robots (SARs) sometimes are perceived as more trustworthy than humans, based on research showing that they are not anticipated as judgmental. Inspired by those evidences, this study aims to assess the success of a SAR as a facilitator for SE lessons for elementary school students. This study conducted two experiments to assess the effectiveness of a SAR in facilitating SE education for elementary school students. We conducted two experiments, a) a group activity in the school classroom where the Nao robot gave a SE lecture, and we evaluated how much information the students acquired from the lecture, and b) an individual activity where the students interacted 1:1 with the robot, and we evaluated their attitudes towards the subject of SE, and if they felt comfortable to ask SE related questions to the robot. Data collected from pre- and post-questionnaires, as well as video annotations, revealed that the SAR significantly improved students' attitudes toward SE. Furthermore, students were more open to asking SE-related questions to the robot than their human teacher. The study emphasized specific SAR characteristics, such as embodiment and non-judgmental behavior, as key factors contributing to their effectiveness in supporting SE education, paving the way for innovative and effective approaches to sexual education in schools.

The advancement in healthcare has shifted focus toward patient-centric approaches, particularly in self-care and patient education, facilitated by access to Electronic Health Records (EHR). However, medical jargon in EHRs poses significant challenges in patient comprehension. To address this, we introduce a new task of automatically generating lay definitions, aiming to simplify complex medical terms into patient-friendly lay language. We first created the README dataset, an extensive collection of over 20,000 unique medical terms and 300,000 mentions, each offering context-aware lay definitions manually annotated by domain experts. We have also engineered a data-centric Human-AI pipeline that synergizes data filtering, augmentation, and selection to improve data quality. We then used README as the training data for models and leveraged a Retrieval-Augmented Generation (RAG) method to reduce hallucinations and improve the quality of model outputs. Our extensive automatic and human evaluations demonstrate that open-source mobile-friendly models, when fine-tuned with high-quality data, are capable of matching or even surpassing the performance of state-of-the-art closed-source large language models like ChatGPT. This research represents a significant stride in closing the knowledge gap in patient education and advancing patient-centric healthcare solutions

How to Do It is Slate's sex advice column. Send it to Stoya and Rich here. My husband and I have an awesome, intelligent 14-year-old son who identifies as bisexual. We are totally accepting and supportive of him. He has had a few short-lived crushes on different genders, though he doesn't seem to be particularly interested in dating right now. His internet search histories are pretty benign--mostly video game stuff, and the occasional search for "hot girls" and "boobs."

Patient portal allows discharged patients to access their personalized discharge instructions in electronic health records (EHRs). However, many patients have difficulty understanding or memorizing their discharge instructions. In this paper, we present PaniniQA, a patient-centric interactive question answering system designed to help patients understand their discharge instructions. PaniniQA first identifies important clinical content from patients' discharge instructions and then formulates patient-specific educational questions. In addition, PaniniQA is also equipped with answer verification functionality to provide timely feedback to correct patients' misunderstandings. Our comprehensive automatic and human evaluation results demonstrate our PaniniQA is capable of improving patients' mastery of their medical instructions through effective interactions